Phylogenetics And Networks for Generalised HIV Epidemics in Africa


MRC Good Health For Women Project

The on-going cohort of high-risk women in Kampala was established in 2008. The rationale for the cohort was the curious lack of data on HIV epidemiology among women involved in high-risk sexual behaviour in Uganda despite the number of groups that have been working on various aspects of the epidemiology of HIV infection. The GHWP was established in one of the larger “red-light-areas” in Kampala. At each 3-monthly visit, data are collected on socio-demographic information among others and blood samples are collected for HIV and other sexually transmitted infections testing. In 2008, an HIV prevalence of 37% was recorded, and a total of 1027 women at high risk were enrolled into a closed cohort. HIV incidence was 3.66/100 person-years (pyr) and declined from 3.66/100 pyr in the first calendar year to 2.24/100 pyr and 2.53/100 pyr in the second and third year respectively. This cohort has since been opened up to enrol a larger number of women who are also encouraged to invite their regular male partners to enrol into the cohort.